Accelerating protein structure determination

Bring your cryo-EM data analysis to the next level by using our cloud platform.

Start using CryoCloud

No installation. No queues. Unlock the full potential of cryo-EM.

Cryo-EM is a Nobel Prize winning method that is revolutionizing biology by providing insights into the 3D architecture of proteins. Better access to cryo-EM infrastructure, faster detectors and improved acquisition schemes have accelerated data aquisition & made cryo-EM more accessible – but at the same time increased the burden on data analysis. Queues, insufficient disk space or even downtime due to failing components can be the consequence, hindering timely results.

CryoCloud is here to address those issues. CryoCloud's web-app provides instant access to cloud resources, image analysis workflows & storage solutions for cryo-EM data analysis. It eliminates queues, downtimes, the need for setup costs & hardware maintenance, while providing optimized & accelerated computation via an intuitive UI. Get started with your data analysis right away: we take care of the setup, so you can focus on your research.

Get started right away

CryoCloud aims to simplify all steps from data to structure, and remove all bottlenecks of data analysis by moving it to the cloud. This removes entry barriers for new researchers and faciliates analysis for everybody. No installation or setup is needed. Just create an account and get started on your data analysis - it’s that simple.

CryoCloud in the front

We have designed a completely new UI that guides you through analysis, yet provides all flexibility and helps you to keep the overview of your projects.

Relion in the back... & more to come!

CryoCloud uses Relion, the gold standard for cryoEM analysis, proven and trusted by the community >10 years – one of many packages to come.


No need for your own HPC, maintenance and IT staff - we have you covered. Stay always up to date with the newest hardware, and choose from a range of packages to cover your needs.


Share results with your colleagues and supervisor. Enable automated reports and review 3D densities within the web-browser. Collaborating on a cryoEM project has never been easier.


With the cloud-resources that we provide, queues are the past. CryoCloud provides on-demand access to the fastest hardware.


No more downtime, connection problems or failed drives. And if something goes wrong, we are there to help - always at your service

Easy Archiving

CryoCloud provides cost-efficient and hassle-free options to archive your published or outdated projects – all at a click of a button.


CryoCloud uses AWS cloud infrastructure, trusted & tested by many biotechs & pharma companies, while our web-app adheres to best practices with regards to data & application security: all data is encrypted & backed up, and strict authentication is applied.

Get access to CryoCloud with just a few clicks and start analysing your cryo-EM data today:

  • Full access to fast cloud resources and our end-to-end cryo-EM analysis workflow via the CryoCloud web-application
  • No queues & fast analysis: jobs are immediately started upon demand on fast cloud resources, allowing e.g. for motion correction of >1,600 K3 movies/ hour (5.6x4k, 75 frames)
  • End-to-end image analysis: CryoCloud provides access to all Relion jobs & more popular packages to come (Topaz, DeepEMhancer, OpenFold)
  • Intuitive UI: we developed a new UI that provides easy monitoring of job hierarchies & flows, allows cloning & queuing of jobs, provides pre-filled input fields & filtering of compatible data formats - all to ensure the smooth & successful completion of jobs
  • Optimized computation: we optimized all jobs to provide fast analysis allowing you to focus on the image analysis
  • Data Uploads: upload data via our standalone CryoCloud uploader running on Windows, Linux & Mac and allowing live data uploads
  • Data Storage: CryoCloud provides storage that grows with your needs and you only pay as much as you use
  • Data Archiving: affordable archiving starting from 2 €/ TB/ month
  • Flexibility: our interface allows easy uploads of external data and downloading of projects, enabling hybrid use of CryoCloud with your existing hardware
  • Teams: Invite & manage your team members via the the CryoCloud web-application and collaborate on projects
  • Data & project management for increased efficiency: keep track of your datasets and projects via our dashboard
  • Pay as much as you need: pick one of various subscriptions based on your needs, with the flexibility to add more users or compute time later

Free 30 day trial

  • Full access to the CryoCloud web-application for Cryo-EM data processing
  • No setup or infrastructure needed
  • 20 hours of compute time
  • 2 TB of storage
  • Access to the CryoCloud Uploader for real-time uploads during data acquisition
Sign up for a Trial

Paid subscription

  • Full access to the CryoCloud web-application for Cryo-EM data processing
  • No setup or infrastructure needed
  • Subscription includes compute hours with various available options to suit the size and needs of your research group
  • Add-ons available to flexibly add more compute hours or users later
  • Access to the CryoCloud Uploader for real-time uploads during data acquisition
  • Pay-per-use storage & archive billed monthly
  • Enterprise solutions available e.g. custom VPC deployment
Prices starting from:
Billed yearly
Billed yearly
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Proudly open source

We believe that open-source fuels innovation, and that transparency and reproducibility is critical for research. CryoCloud is a commercial application and provides instant access to commercial cloud services, but in the near future we intend to make many parts of our platform open-source and available under a permissive license.

Robert Englmeier, PhDStructural Biologist, Co-Founder & CEO

9y+ of applied cryoEM experience working at multiple research institutes

Ilya GubinsComputer Scientist, Co-Founder & CTO

10y+ experience in software development, including image analysis and machine learning

Boy PersoonFull Stack Engineer, Co-Founder & CPO

8y+ of industry experience working with Startups, NGOs and EU projects

Carolyn Langen, PhDLead Software Engineer

Anna BoroninaML Engineer


We are open to collaborations with biotech companies, and can arrange access to a network of cryoEM facilities and research partners.

Please get in touch with us if you want to discuss how to leverage cryoEM for your research.

Plan a Demo

We'd love to hear about your requirements, get feedback or plan a demo with you. You can easily plan a meeting here.


Want to know more? Please feel free to drop us a message at